A drug used alone or with other drugs to treat certain types of non-small cell lung cancer and malignant pleural mesothelioma. It is also being studied in the treatment of other types of cancer. Pemetrexed disodium stops cells from using folic acid to make DNA and may kill cancer cells. It is a type of antimetabolite and a type of antifolate. Also called Alimta, LY231514, and Pemfexy. US Brand Name(s) Alimta, Pemfexy. FDA Approved: Yes
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Pemetrexed is used to treat certain types of cancer (such as lung cancer, mesothelioma). It is a chemotherapy drug that works by slowing or stopping the growth of cancer cells.
In February 2004, the U.S. Food and Drug Administration (FDA) approved pemetrexed for treatment of malignant pleural mesothelioma, a type of tumor of the mesothelium, the thin layer of tissue that covers many of the internal organs, in combination with cisplatin for patients whose disease is either unresectable or who are not otherwise candidates for curative surgery. In September 2008, the FDA granted approval as a first-line treatment, in combination with cisplatin, against locally advanced and metastatic non-small cell lung cancer (NSCLC) in patients with non-squamous histology.