ATGAM Sterile Solution contains lymphocyte immune globulin, anti-thymocyte globulin [equine]. It is the purified, concentrated, and sterile gamma globulin, primarily monomeric IgG, from hyperimmune serum of horses immunized with human thymus lymphocytes. ATGAM is a transparent to slightly opalescent aqueous protein solution. It may appear colorless to faintly pink or brown and is nearly odorless
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Renal Transplantation
ATGAM Sterile Solution is indicated for the management of allograft rejection in renal
transplant patients. When administered with conventional therapy at the time of rejection,
it increases the frequency of resolution of the acute rejection episode.
Aplastic Anemia
ATGAM is indicated for the treatment of moderate to severe aplastic anemia in patients
who are unsuitable for bone marrow transplantation.
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the pathogen, called an antigen.
lymphocyte immune globulin
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