A drug used to treat adults with myelodysplastic syndromes, including chronic myelomonocytic leukemia. It is also being studied in the treatment of other types of cancer. Decitabine stops cells from making DNA and may kill cancer cells. It is a type of antimetabolite. Also called Dacogen.
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Decitabine is approved to treat adults with: Myelodysplastic syndromes (MDS), including chronic myelomonocytic leukemia (CMML). Decitabine, sold under the brand name Dacogen among others, acts as a nucleic acid synthesis inhibitor. It is a medication for the treatment of myelodysplastic syndromes, a class of conditions where certain blood cells are dysfunctional, and for acute myeloid leukemia (AML). Chemically, it is a cytidine analog.