A drug used to treat adults with B-cell acute lymphoblastic leukemia that has come back or has not gotten better with other treatment. It is also being studied in the treatment of other types of cancer. Inotuzumab ozogamicin contains a monoclonal antibody that binds to a protein called CD22, which is found on some leukemia cells. It also contains an anticancer drug, which may help kill cancer cells. Inotuzumab ozogamicin is a type of antibody-drug conjugate. Also called Besponsa. US Brand Name(s): Besponsa. FDA Approved: Yes
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Inotuzumab ozogamicin, sold under the brand name Besponsa, is an antibody-drug conjugate medication used to treat relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL). The medication consists of a humanized monoclonal antibody against CD22 (inotuzumab), linked to a cytotoxic agent from the class of calicheamicins called ozogamicin.
Use in Cancer
Inotuzumab ozogamicin is approved to treat:
B-cell acute lymphoblastic leukemia (ALL). It is used in adults whose disease has relapsed or is refractory (does not respond to treatment).
Inotuzumab ozogamicin is also being studied in the treatment of other types of cancer.