Linagliptin is used along with diet and exercise and sometimes with other medications to lower blood sugar levels in patients with type 2 diabetes (condition in which blood sugar is too high because the body does not produce or use insulin normally). Linagliptin is in a class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors
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Linagliptin, sold under the brand name Trajenta among others, is a medication used to treat diabetes mellitus type 2. It is generally less preferred than metformin and sulfonylureas as an initial treatment. It is used together with exercise and diet. It is not recommended in type 1 diabetes.
Linagliptin was approved for medical use in the United States in 2011. In 2018, it was the 177th most commonly prescribed medication in the United States, with more than 3 million prescriptions. As of August 2021, linagliptin is available as a generic medicine in the US.