A drug used alone or with other drugs to treat certain adults with acute myeloid leukemia that is newly diagnosed and adults with chronic lymphocytic leukemia or small lymphocytic lymphoma. It is also being studied in the treatment of other types of cancer. Venetoclax binds to a protein called BCL2, which is found on some types of cancer cells. Blocking this protein may help kill cancer cells and may make them more sensitive to anticancer drugs. Venetoclax is a type of BCL2 inhibitor. Also called Venclexta. US Brand Name(s): Venclexta. FDA Approved: Yes
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This medication is used to treat certain types of cancer (chronic lymphocytic leukemia-CLL, small lymphocytic lymphoma-SLL, acute myeloid leukemia-AML). Venetoclax is a drug that works by helping to slow or stop the growth of cancer cells.
Venetoclax is approved to treat:
- Acute myeloid leukemia that is newly diagnosed. It is used in adults aged 75 years and older or adults who cannot be treated with intensive induction chemotherapy. It is given with either azacitidine, decitabine, or low-dose cytarabine.
- Chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) in adults. It may be given alone or with either obinutuzumab or rituximab.