A drug used to treat high levels of uric acid in the blood of adults and children with leukemia, lymphoma, or other types of cancer who are receiving certain types of anticancer therapy. Uric acid is a natural substance that can build up in the blood as tumors break down. Rasburicase helps break down and remove uric acid from the body. It is a type of recombinant enzyme and a type of urate-lowering drug. Also called Elitek and recombinant urate oxidase.
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Rasburicase is approved for use by the U.S. Food and Drug Administration (and European counterparts) for the prevention and treatment of tumor lysis syndrome (TLS) in people receiving chemotherapy for hematologic cancers such as leukemias and lymphomas. However, it is not clear if it results in important benefits such as decreased kidney problems or decreased risk of death as of 2017.
Rasburicase is approved to treat adults and children with:
High levels of uric acid in the blood.
Rasburicase is also approved to prevent:
Tumor lysis syndrome