A drug used to treat Hodgkin lymphoma that did not get better with other anticancer drugs and melanoma that has spread to other parts of the body. It is also being studied in the treatment of other types of cancer. Dacarbazine damages the cell’s DNA and may kill cancer cells. It is a type of alkylating agent.
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Dacarbazine (DTIC), also known as imidazole carboxamide, is a chemotherapy medication used in the treatment of melanoma and Hodgkin’s lymphoma. For Hodgkin’s it is often used together with vinblastine, bleomycin, and doxorubicin. It is given by injection into a vein.
Use in Cancer
Dacarbazine is approved to be used alone or with other drugs to treat:
Hodgkin lymphoma in patients whose disease has not gotten better with other chemotherapy.
Melanoma that has metastasized (spread to other parts of the body).
Dacarbazine is also being studied in the treatment of other types of cancer.