A drug used to treat certain types of breast cancer, choriocarcinoma (a type of gestational trophoblastic tumor), Hodgkin lymphoma, non-Hodgkin lymphoma, Kaposi sarcoma, mycosis fungoides (a type of cutaneous T-cell lymphoma), and testicular cancer. It is also being studied in the treatment of other types of cancer. Vinblastine sulfate stops cancer cells from growing and dividing and may kill them. It is a type of vinca alkaloid. The brand name Velban has been taken off the market and is no longer available.
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Vinblastine is a component of a number of chemotherapy regimens, including ABVD for Hodgkin lymphoma. It is also used to treat histiocytosis according to the established protocols of the Histiocytosis Association.
Use in Cancer
Vinblastine sulfate is approved as palliative treatment for:
Breast cancer that has not gotten better with other treatment. It is used in adults.
Choriocarcinoma (a type of gestational trophoblastic disease) that has not gotten better with other chemotherapy. It is used in adults.
Hodgkin lymphoma. It is used in adults and children with advanced disease.
Kaposi sarcoma. It is used in adults.
Mycosis fungoides (a type of cutaneous T-cell lymphoma). It is used in adults.
Non-Hodgkin lymphoma (NHL) in adults.
Testicular germ cell tumors. It is used in adults and children with advanced disease.